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Updated: Jun 5, 2025

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

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在T细胞激活蛋白表面的V-域免疫球蛋白抑制剂上绘制结合热点和短暂的结合口袋

Bingjie Li1, Lixiu Xu1, Chu Chen1

  • 1School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, China.

ACS omega
|December 16, 2024
PubMed
概括

确定V-域免疫球蛋白抑制T细胞激活 (VISTA) 的关键相互作用点对于开发新的癌症疗法至关重要. 这项研究绘制了VISTA/VSIG-3热点地图,揭示了新型免疫检查点抑制剂的潜在目标.

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