辐射引起的鼻炎:机制研究和临床进展审查
Chunge Zheng1, Longgang Yu2, Yan Jiang1
1Department of Otolaryngology, Head and Neck Surgery The Affiliated Hospital of Qingdao University Qingdao Shandong Province China.
World journal of otorhinolaryngology - head and neck surgery
|December 16, 2024
概括
辐射诱导的鼻炎,在头癌患者中经常被忽视,可在放射治疗后持续存在. 虽然有治疗方法,但没有统一的协议提供显著的改善,需要进一步的研究.
科学领域:
- 在瘤学瘤学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 辐射瘤学 辐射瘤学
背景情况:
- 辐射诱导的鼻炎是在接受放射治疗的头癌患者中具有显著的剂量限制毒性.
- 这种情况在临床上经常被忽视,与口腔粘膜炎相比,在研究中代表性不足.
研究的目的:
- 审查当前关于辐射诱导鼻炎的文献,涵盖其病变发生,临床表现,预测因素,治疗和预后.
主要方法:
- 在PubMed上进行了全面的文献搜索,并对1995年至2022年间发表的研究进行了参考列表.
- 关键词包括"电离辐射"",放射治疗"",头瘤"和"辐射诱导的鼻炎".
- 包括详细介绍病情各个方面的全文文章.
主要成果:
- 辐射诱导的鼻炎可以在放射治疗期间发生,并且在放射治疗后持续很长时间,原因是细胞损伤和组织损伤.
- 透视鼻手术可能有助于症状,但存在风险;鼻灌,类固醇和抗生素提供部分缓解.
- 实验药物正在研究中,但尚未临床应用.
结论:
- 辐射引起的鼻炎是一种可控的毒性,但可能是严重的.
- 目前存在预防和治疗策略,但缺乏统一的管理协议.
- 进一步的研究对于改善患者的治疗结果至关重要.
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