用于预测威尔姆斯瘤手术风险和结果的CT图像参数
Supika Kritsaneepaiboon1, Tanasap Rukkito1, Pattama Tanaanantarak1
1Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, THA.
Cureus
|December 16, 2024
概括
术前CT扫描发现,如腹腔大动脉封闭,上腺参与和瘤溢出,可以预测威尔姆斯瘤 (WT) 患者的手术风险和结果. 这些成像标记器有助于外科医生规划和执行更好的患者管理程序.
科学领域:
- 放射学 放射学是一门学科.
- 儿科瘤学 儿科瘤学
- 手术风险评估手术风险评估
背景情况:
- 威尔姆斯瘤 (WT) 是一个常见的儿科癌.
- 准确预测手术风险和结果对于有效的WT管理至关重要.
- 术前成像在WT的手术规划中发挥着至关重要的作用.
研究的目的:
- 在计算机断层扫描 (CT) 上确定术前成像参数,以预测威尔姆斯瘤 (WT) 的手术风险和结果.
主要方法:
- 55名WT患者的队列被分为外科低风险 (SLR) 和外科高风险 (SHR) 组.
- 分析了CT成像发现与外科手术风险因素的相关性.
- 进行了生存分析,以评估成像参数对无病生存时间 (DFS) 的影响.
主要成果:
- 在SLR和SHR组之间观察到CT参数的显著差异 - - 腹腔大动脉封闭,上腺参与和瘤溢出 (p <0.05).
- 这三个CT参数独立地与手术风险增加有关 (ORs从7.61到55.57).
- 上腺干扰和瘤溢出被确定为较差生存率的放射学预测因素.
结论:
- 腹腔大动脉封闭,上腺参与和瘤泄漏的术前CT发现是WT手术风险和结果的强有力的预测指标.
- 这些成像参数可以帮助外科医生优化WT患者的手术前准备和手术内决策.
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