通过皮肤托与芬太尼补丁治疗疼痛治疗剖腹产后:一个比较的,随机的,双盲研究
Sandip Baheti1, Sharan Muruganantham1
1Department of Anaesthesiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Cureus
|December 16, 2024
概括
通过皮肤注射的洛芬贴片在剖腹产后提供了与芬太尼贴片相比较的术后疼痛缓解,随着洛芬的使用,观察到提高了警觉性和减少了昏昏欲睡.
科学领域:
- 麻醉学和疼痛管理
- 药理学 药理学是指药理学的学科.
- 产科 产科 产科 产科 产科
背景情况:
- 在剖腹产后有效的术后疼痛管理对于母亲的康复和婴儿的结合至关重要.
- 透皮贴片比口服止痛药具有优势,包括控制分娩和避免第一通代谢.
- 优化疼痛控制可以促进更顺的产后恢复和康复.
研究的目的:
- 为了比较通过皮肤给予的托与通过皮肤给予的芬太尼在剖腹产后的术后疼痛管理中的疗效和安全性.
- 为了评估疼痛得分,需要救援止痛,以及接受两种补丁的分娩者镇静水平.
主要方法:
- 一项随机,双盲,比较性研究,涉及70名ASA II分娩患者,在脊髓麻醉下进行剖腹产.
- 患者被随机分配,在麻醉后立即接受一种通过皮肤注射的凯托 (30毫克) 或一种通过皮肤注射的芬太尼尔 (25毫克) 的贴片.
- 使用视觉模拟量表 (VAS) 评估疼痛,使用里士满兴奋镇静量表 (Richmond Agitation-Sedation Scale) 在24小时内评估镇静.
主要成果:
- 两个贴片在手术后的最初12小时内提供了相似的止痛效果.
- 与芬太尼相比,通过皮肤注射的甲在术后16小时和20小时表现出优异的止痛效果.
- 较少的患者需要使用烯进行救援止痛,而烯组患者在24小时内表现出明显减少的嗜睡和不安.
结论:
- 透皮基托 (30毫克) 和芬太尼 (25毫克) 贴片在剖腹产后提供有效的术后止痛.
- 与芬太尼相比,罗贴片在术后几个小时内显示出更好的疗效和更好的镇静概况.
- 通过皮肤注射的甲可能是剖腹产术后疼痛管理的首选选择,因为它的疗效和有利的镇静特性.
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