在人类中应用高电流时间干扰电刺激的安全性和有效性
Yan Wang1,2, Ginger Qinghong Zeng3, Mengmeng Wang1,2
1School of Mental Health, Bengbu Medical University, Bengbu, China.
Frontiers in human neuroscience
|December 16, 2024
概括
高电流时间干扰 (TI) 电刺激对人类大脑刺激是安全有效的. 这种方法区分了β和gamma振荡在运动功能的作用,推进了大脑刺激研究.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 电气工程 电气工程
背景情况:
- 时间干扰 (TI) 电刺激为焦点深度大脑准提供了希望.
- 目前,有限的电场强度正在挑战TI的有效性.
研究的目的:
- 引入高电流TI电刺激协议以提高强度.
- 评估高电流TI对人类初级运动皮层 (M1) 刺激的安全性和有效性.
主要方法:
- 安全性通过生物化学,神经心理测试和EEG记录在30分钟TI刺激 (20Hz,70Hz,假) 之前/之后进行评估.
- 使用简单反应时间 (SRT) 和单增量运动任务来评估效率.
- 贝塔 (20 Hz) 和玛 (70 Hz) 振荡在运动功能的研究作用.
主要成果:
- 安全性评估没有显著差异;没有检测到活动.
- 20 Hz TI刺激延迟反应时间在一个增量任务中.
- 70 Hz TI 刺激显示了在 SRT 任务中提高性能的趋势.
结论:
- 高电流TI电刺激对人类大脑刺激是安全有效的.
- 清晰的运动任务效应突出显示了β和gamma振荡的分离作用.
- 为未来大脑刺激研究中的高电流TI应用提供了洞察力.
相关概念视频
Household Wiring And Electrical Safety
Companies that supply power to most modern households use three conductors, typically called a three-wire line. While one is neutral, the other two are both at 120 V but with opposite polarity, giving a voltage of 240 V between them. With a three-wire line, high-power appliances that require 240 V, such as electric stoves and clothes dryers, are linked between the two hot lines. 120 V appliances can be connected between the neutral and either of the hot lines. The neutral side, which is always...
Induced Electric Fields: Applications
An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
Insulation Coordination
Insulation coordination is the process of matching electric equipment's insulation strength with protective device characteristics to protect the equipment against expected overvoltages. This selection is based on engineering judgment and cost. Equipment can generally withstand short-duration high transient overvoltages, but repeated tests with identical waveforms can yield inconsistent results. As a result, standard impulse voltage waveforms are used for testing, defined by specific times for...
Circuit Breaker and Fuse Selection
A circuit breaker is a device engineered to interrupt fault currents and sometimes reclose automatically. When a fault current is detected, the breaker separates the electrical contacts, which generates an arc. This arc is extinguished by methods such as elongation, cooling, or splitting, depending on the breaker's design. Breakers are categorized based on the voltage they operate at and the medium used for arc extinction, such as air, oil, SF6 gas, or vacuum.
In high-voltage systems, circuit...
In high-voltage systems, circuit...


