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Updated: Jun 5, 2025

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Published on: January 22, 2019

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通过HIV-1编码的反意义转录来对潜伏逆转进行表观遗传沉默和阻断

Rui Li, Kaveh Daneshvar, Xinjie Ji

    bioRxiv : the preprint server for biology
    |December 16, 2024
    PubMed
    概括

    一个HIV-1反意义转录 (AST) 通过创建一个封闭的染色质状态来强制执行病毒延迟. 这种生物分子通过阻断延迟逆转,显示出HIV-1治愈疗法的潜力.

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