相关实验视频

Updated: Jun 5, 2025

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues
07:10

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues

Published on: February 19, 2019

8.8K

一个E.E.中的动态异质性. 大肠杆菌应激反应调节器调节基因激活和抗菌素耐受性

Caroline M Blassick, Jean-Baptiste Lugagne, Mary J Dunlop

    bioRxiv : the preprint server for biology
    |December 16, 2024
    PubMed
    概括

    细菌应激反应基因异质性影响药物耐药性. 控制PhoP表达揭示了下游基因如何保护细菌,PmrD表达对Polymyxin B.至关重要.

    更多相关视频

    DNA-affinity-purified Chip DAP-chip Method to Determine Gene Targets for Bacterial Two component Regulatory Systems12:24

    DNA-affinity-purified Chip DAP-chip Method to Determine Gene Targets for Bacterial Two component Regulatory Systems

    Published on: July 21, 2014

    16.7K
    Quantification of the Abundance and Charging Levels of Transfer RNAs in Escherichia coli10:34

    Quantification of the Abundance and Charging Levels of Transfer RNAs in Escherichia coli

    Published on: August 22, 2017

    9.3K

    相关概念视频

    Constitutive and Regulated Gene Expression01:27

    Constitutive and Regulated Gene Expression

    Gene expression in prokaryotes is governed by constitutive and regulated systems, allowing cells to balance the production of essential proteins with adaptive responses to environmental changes.Constitutive Gene ExpressionConstitutive, or housekeeping, genes are continuously expressed as they encode proteins vital for fundamental cellular processes. These include enzymes for glycolysis, ribosomal components for protein synthesis, and proteins involved in DNA replication. Their constant...
    Gene Regulation in Microbial Communities: Quorum Sensing01:28

    Gene Regulation in Microbial Communities: Quorum Sensing

    Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
    1
    Inducible Operons: lac Operon01:25

    Inducible Operons: lac Operon

    The lac operon in Escherichia coli is a model for understanding inducible gene regulation and metabolic flexibility. It integrates local control by lactose and global regulation through catabolite repression, enabling E. coli to preferentially metabolize glucose when available and switch to lactose utilization when glucose is scarce.Structure and Function of the lac OperonThe lac operon contains three structural genes: lacZ (β-galactosidase), lacY (lactose permease), and lacA...
    7
    Prokaryotic Transcriptional Activators and Repressors01:58

    Prokaryotic Transcriptional Activators and Repressors

    The organization of prokaryotic genes in their genome is notably different from that of eukaryotes. Prokaryotic genes are organized, such that the genes for proteins involved in the same biochemical process or function are located together in groups. This group of genes, along with their regulatory elements, are collectively known as an operon. The functional genes in an operon are transcribed together to give a single strand of mRNA known as polycistronic mRNA.
    Transcription of prokaryotic...
    20.8K