慢性腹腔穿刺后头痛 - - 腰部穿刺后的一种严重且被低估的并发症:一项队列研究
Luisa Mona Kraus1,2, Levin Häni1,3, Amir El Rahal1
1Department of Neurosurgery, Medical Center, University Hospital Freiburg, Freiburg im Breisgau, Germany.
Frontiers in neurology
|December 16, 2024
概括
慢性痛后刺痛头痛 (cPDPH) 是一种严重的,报告不足的疾病,导致严重的疾病负担. 这项研究强调了cPDPH对患者社会和工作生活的深远影响,需要进一步研究.
科学领域:
- 神经学 神经学
- 麻醉学 麻醉学
- 疼痛医学 医学 疼痛医学
背景情况:
- 持续性穿刺后头痛 (PDPH) 通常被认为是腰部穿刺的轻微并发症.
- 目前的诊断标准 (ICHD-3) 不会考虑持续超过14天的头痛或外周血补丁 (EBP) 后的头痛.
- 这项研究解决了与持续性刺穿后持续性头痛相关的重大疾病负担.
研究的目的:
- 为了研究慢性痛后刺痛头痛 (cPDPH) 的特征和影响.
- 突出在临床实践中对cPDPH的报告不足和忽视.
- 强调需要对这种严重疾病进行进一步研究.
主要方法:
- 对患者进行了回顾性单中心分析,这些患者患有持续性刺痛和静止性头痛,持续时间超过14天,耐受于EBP.
- 通过专门的调查问卷评估社会经济因素和患者病史.
- 包括30名被诊断患有cPDPH的患者.
主要成果:
- 患者经历了平均31天的住院护理和381天的病假.
- 患者为他们的cPDPH咨询了平均5名不同的医生/机构.
- 所有患者都报告cPDPH对他们的社会和工作生活产生了重大负面影响.
结论:
- 慢性痛后刺痛头痛 (cPDPH) 经常被忽视和低估.
- cPDPH导致长时间住院和严重损害社会和工作功能.
- 需要进一步的前性研究来了解和管理这种严重的疾病.
相关概念视频
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...


