血液学参数和相关因素的比较,乳腺癌和没有乳腺癌的妇女:一个病例对照研究
Abdul Baset Abbas1,2, Shima Al-Gamei2, AmatAlraheem Naser2
1Medical Laboratories Department, Faculty of Medicine and Health Sciences, Ibb University, Ibb City, 70270, Yemen.
Breast cancer (Dove Medical Press)
|December 16, 2024
概括
血红蛋白和白细胞计数等血液学参数在患有乳腺癌 (BC) 的女性中显示出显著的差异. 这些发现表明它们在BC监测和诊断中的潜在作用.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 乳腺癌 (BC) 是全球癌症相关死亡的主要原因.
- 血液学参数经常用于诊断各种健康状况.
- 这项研究调查了血液学概况与女性乳腺癌状况之间的关联.
研究的目的:
- 为了评估乳腺癌妇女和健康对照者之间全血细胞计 (CBC) 参数的差异.
- 探索血液学参数作为乳腺癌监测生物标志物的潜力.
主要方法:
- 一项涉及100名患有乳腺癌的女性和100名健康对照者的病例控制研究.
- 血液样本被分析为完整血清 (CBC) 参数.
- 统计分析包括t测试,曼-惠特尼和奇平方测试 (P≤0.05被认为是显著的).
主要成果:
- 在年龄,体重,居住地,就业,经济地位,教育,运动和饮食方面,观察到群体之间的显著差异.
- 诸如婚姻状况,结婚年龄,出生人数和避孕药使用等生殖因素也显示出显著的差异.
- 主要的血液学参数包括血红蛋白 (Hb),红细胞 (RBC) 计数,白细胞 (WBC) 计数,中性粒细胞,淋巴细胞和单细胞在BC患者和对照人群之间有显著差异.
结论:
- 血液学参数如Hb,红细胞,白细胞,中性粒细胞,淋巴细胞和单细胞在患有乳腺癌的女性中显示出显著的差异.
- 这些发现凸显了特定血液学参数在乳腺癌监测中的潜在实用性.
- 建议在癌症治疗 (化疗或乳腺切除术) 期间和之后进行进一步的研究,以评估这些参数.
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