血清塞斯特林2和fetuin-A与肺结核患者的早期肺部参与有关:一个横截面研究
Qian Li1, Yanyan Yu2, Fen Gao1
1Department of Tuberculosis Internal Medicine II, Hunan Chest Hospital, Changsha, China.
Journal of thoracic disease
|December 16, 2024
概括
血清塞斯特林2和fetuin-A水平可以帮助诊断肺结核患者早期的肺部参与. 较高的塞斯特林2和较低的费图因-A表明肺部疾病,有助于及时治疗.
科学领域:
- 肺部医学 肺部医学
- 生物化学 生物化学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 结核性肺炎是一种常见的肺外结核病形式.
- 早期诊断和管理对于患者的治疗结果至关重要.
- 识别早期膜干预的生物标志物是必不可少的.
研究的目的:
- 评估血清中塞斯特林2和费图因-A水平,作为肺结核早期肺部参与的潜在生物标志物.
- 评估这些生物标志物的诊断性能.
主要方法:
- 在136名肺结核患者的横截面研究.
- 测量了血清中的塞斯特林2和费图因-A水平.
- 通过胸部CT扫描诊断的多叶膜干扰,并将组之间进行比较.
- 进行了物流回归和ROC曲线分析.
主要成果:
- 患有膜干扰的患者的血清塞斯特林2水平较高,血清费图因-A水平较低.
- 这两种生物标志物都与膜干扰有显著的关联.
- 组合塞斯特林2和fetuin-A显示出最佳的诊断性能.
结论:
- 血清塞斯特林2的升高和血清费图因-A水平的降低表明肺结核的肺部早期参与.
- 这些生物标志物可以帮助早期诊断和治疗结核性多炎.
相关概念视频
Pulmonary Tuberculosis IV
133
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
133
Pulmonary Tuberculosis III
303
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
303
Pulmonary Tuberculosis II
211
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
211
Pulmonary Tuberculosis I
220
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
220
Pulmonary Tuberculosis V
170
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
170
Pleural Effusion II: Symptoms and Management
154
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
154


