恶性肺结节的精确诊断和预后评估:叙述性综述
Miaomiao Wen1, Qian Zheng2,3, Xiaohong Ji1
1Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Journal of thoracic disease
|December 16, 2024
概括
准确识别恶性肺结节 (PNs) 对于有效治疗至关重要. 本综述探讨了使用临床病理学特征,液体活检和人工智能的PN早期检测,个性化治疗和预后预测方面的进展.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 放射学 放射学是指放射学
背景情况:
- 肺结节 (PNs) 是肺膜中的小不透明点,恶性结节占病例的5%.
- 低剂量计算机断层扫描 (LDCT) 增加了PN检测,但由于预后异质性,管理这些结节会带来挑战.
- 准确区分良性和恶性PN和风险分层是临床的关键需求.
研究的目的:
- 审查恶性PNS的临床管理方面的研究进展.
- 探索早期检测,个性化治疗和PNS的预后预测方面的进展.
- 突出精准医学在管理恶性PNS中的作用.
主要方法:
- 关于识别和预测PNS早期肺癌的诊断方法的文献综述.
- 检查经典临床病理学特征,液体活检和人工智能 (AI).
主要成果:
- 患有PN的早期肺癌的年度检测率正在上升.
- 经典的临床病理学特征对于诊断和预后很重要.
- 液体活检和人工智能显示了在PN管理中方便和准确性的承诺.
结论:
- 精准医学对于管理恶性PNS至关重要.
- 临床病理学特征,液体活检和人工智能有助于早期检测,个性化治疗和预后预测.
- 这些方法可以改善PNS患者的临床结果.
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