美国退伍军人肺外结核的危险因素,1990-2022年
Gina Oda1, Cynthia Lucero-Obusan1, Patricia Schirmer1
1US Department of Veterans Affairs, Public Health National Program Office, Washington, DC, and Palo Alto, California, USA.
Open forum infectious diseases
|December 16, 2024
概括
患有活跃结核病的美国退伍军人面临肺外结核病 (EPTB) 的风险. 非西班牙裔黑人种族,糖尿病,艾滋病毒,病和早期死亡率是EPTB的关键风险因素.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战.
- 肺外结核 (EPTB) 呈现出诊断和治疗的复杂性.
- 确定EPTB的风险因素对于有针对性的干预至关重要.
研究的目的:
- 确定与美国退伍军人肺外结核 (EPTB) 相关的人口和临床因素.
- 在这个人群中,比较EPTB与肺结核的风险因素.
主要方法:
- 美国退伍军人实验室确诊结核病的回顾性队列研究 (1990-2022年).
- 多变量物流回归分析以确定风险因素与EPTB之间的关联.
- 分析包括人口统计数据和临床变量.
主要成果:
- 7493名退伍军人中有19%患有EPTB;肺结核是最常见的.
- 独立的EPTB风险因素包括非西班牙裔黑人种族/种族,糖尿病,艾滋病毒感染和严重的病.
- 结核性脑膜炎的90天死亡率最高.
结论:
- 确定了美国退伍军人EPTB的几个关键风险因素.
- 医疗保健提供者需要对识别EPTB风险人群的教育.
- 早期诊断和治疗EPTB对于预防严重后果至关重要.
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