预制体外膜氧化的临床实践:安全性,无菌性和功能性
Mauro Renghini1, Debora Maddinelli1, Anna Papeo2
1From the Division of Cardiothoracic Department-Perfusion Unit, Azienda Socio Sanitaria Territoriale Spedali Civili, Brescia, Italy.
概括
预制的体外膜氧化 (ECMO) 电路对于临床使用是安全有效的. 储存的无菌电路显示出最小的污染,确保在紧急情况下可靠的功能.
科学领域:
- 心血管科学 心血管科学
- 医疗工程 医疗工程
- 关键护理医学 关键护理医学
背景情况:
- 身体外膜氧化 (ECMO) 提供了重要的心肺呼吸支持.
- 标准ECMO电路的准备可能耗时,在紧急情况下会带来挑战.
- 预装ECMO电路为快速部署提供了一个潜在的解决方案.
研究的目的:
- 评估预制ECMO电路的无菌性,功能性和安全性.
- 评估长期储存对预制ECMO电路完整性的影响.
- 为了确定预装配和预制成的ECMO电路的临床实用性.
主要方法:
- 在5年内对223个预制ECMO电路进行了回顾性分析.
- 在准备,每周和植入前进行无菌性和功能性测试.
- 在无菌环境中连续循环循环,直到使用.
主要成果:
- 在570个样本中,只有2个 (0.3%) 显示有细菌污染.
- 所有植入的电路都保持了令人满意的气体传输和早期功能.
- 最长的存储周期 (73天) 没有产生任何阳性培养.
结论:
- 预制的ECMO电路具有很高的安全性和可靠性.
- 标准化的预制和储存协议将污染风险降至最低.
- 预制的ECMO电路增强了临床实践,特别是在紧急情况下.
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