相关实验视频
Updated: Jun 5, 2025

07:56
Measuring Skeletal Muscle Thermogenesis in Mice and Rats
Published on: July 27, 2022
2.9K
可穿戴式温度传感器增强的挥发力学技术,用于快速方便地检测后生性肉毒
Xiaoyang Li1, Yufei Yan2, Chenyi Hu1
1State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, 100071, China.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|December 16, 2024
概括
这项研究引入了一种新的方法,使用可穿戴温度传感器和呼吸分析来检测注射肉毒神经毒素 (BoNT) 的副作用. 这种方法可以准确地识别身体不适的早期迹象,提高患者的安全性.
科学领域:
- 生物医学工程 生物医学工程
- 分析化学 分析化学
- 毒理学 毒理学 毒理学
背景情况:
- 评估注射肉毒神经毒素 (BoNT) 的副作用是一项挑战.
- 早期发现阳性肉毒主义和相关的身体不适对于患者的管理至关重要.
研究的目的:
- 开发一种创新,快速和方便的方法来预测BoNT注射后的身体不适.
- 为了确定特定的挥发性有机化合物 (VOC) 作为BoNT中毒的生物标志物.
主要方法:
- 将可穿戴式温度传感器与生物相容的甲基化凝 (GelMA) 薄膜集成.
- 使用手持式呼吸分析仪与基于伊稳定 (YSZ) 的气体传感器阵列.
- 同时监测呼吸中的挥发性有机化合物 (VOC) 和体温波动.
主要成果:
- 识别了五种VOC (乙,烯,乙醇,2-,n-butan) 作为BoNT中毒的潜在标志物.
- 动物初步测试表明,在早期检测BoNT相关的身体不适时,准确度超过91.2%.
- 验证集成可穿戴传感器和挥发力学方法.
结论:
- 开发的综合方法对早期识别与BoNT相关的问题有很大的前景.
- 这一进步使得接受BoNT注射的患者能够及时进行干预,并改善了治疗策略.
- 穿戴式传感和 volatilomics 的结合为监测治疗副作用提供了一个新的范式.
相关概念视频
Equipments Used to Measure Body Temperature
960
Body temperature can be assessed using various devices and measured in Celsius or Fahrenheit.
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...
960
Temperature Measurement Sites
1.5K
A thermometer measures body temperature. The common sites for measuring body temperature are the oral cavity, axillary region, temporal artery, and skin surface, such as the forehead, abdomen, and axilla. True core body temperature is assessed in the rectum, tympanic membrane, pulmonary artery, esophagus, and urinary bladder.
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...
1.5K
Assessing Body Temperature - Temporal Artery
521
Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's...
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's...
521
Assessing Body Temperature - Oral
726
Here are the steps to accurately measure oral temperature using an electronic thermometer:
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
726
Assessing Body Temperature - Axilla
575
Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
575
Assessing Body Temperature - Tympanic membrane
565
Assessing tympanic membrane temperature involves using a tympanic membrane thermometer (TMT). Here is a step-by-step guide:
Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
565

