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在N蛋白中SARS-CoV-2的特定适应抑制NF-κB的激活和改变病变发生

Xiao Guo1, Shimin Yang1, Zeng Cai2

  • 1State Key Laboratory of Virology, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China.

The Journal of cell biology
|December 16, 2024
PubMed
概括

与SARS-CoV-2核体蛋白质不同,SARS-CoV-2核体蛋白质阻断核因子-κB (NF-κB) 途径的激活,与SARS-CoV核体蛋白质不同. 在SARS-CoV-2中,特定的氨基酸变化是这种病原性差异的关键.

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