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Updated: Jun 5, 2025

Author Spotlight: Imaging ATG9A, a Multi-Spanning Membrane Protein
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Author Spotlight: Imaging ATG9A, a Multi-Spanning Membrane Protein

Published on: June 16, 2023

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由于V-ATPase亚单元V0a2的功能丧失而导致的高尔基 pH 升高与组织特异的糖化变化和环精子症相关

Johannes Kopp1,2,3, Denise Jahn1,2,4, Guido Vogt1,2

  • 1Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Institute of Medical Genetics and Human Genetics, 13353, Berlin, Germany.

Cellular and molecular life sciences : CMLS
|December 16, 2024
PubMed
概括

在ATP6V0A2中的功能丧失变体会导致纹皮肤综合征 (WSS). 这项研究揭示了WSS涉及改变的O-糖化和跨戈尔吉pH值,影响皮肤,神经元迁移和男性生育能力.

关键词:
在Cutis laxaxa中使用.全球动物精子.葡萄糖基酶化是指葡萄糖基酶化.戈尔吉戈尔吉是一座古老的城市.神经元迁移的神经元迁移精子发生是精子生成.这是一个V-ATPase.囊泡性人口贩运活动调节pH值的方法

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