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Updated: Jun 5, 2025

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
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Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark

Published on: January 26, 2018

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Evi1控制着Kdm6b介导的组素去甲基化,以调节血造原生细胞中Laptm4b驱动的mTOR通路

Qiong Wu1,2, Chunjie Yu2, Fang Yu2

  • 1Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.

The Journal of clinical investigation
|December 16, 2024
PubMed
概括

在小鼠中,异型病毒整合部位1 (EVI1) 过度表达会通过扩大髓状原始体和通过KDM6B/H3K27me3/LAPTM4B通路抑制淋巴发育,导致MDS/MPN类疾病.

关键词:
血液学 血液学 血液学造血干细胞 造血干细胞 造血干细胞白血病 (Leukemias) 是一种癌症.

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