测试阿尔茨海默病预测预测的认知正常.
1Department of Geriatrics and State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Journal of neurochemistry
|December 16, 2024
概括
早期的阿尔茨海默氏症诊断是关键. 一项研究将血乙卡尼丁 (ACs) 与β-粉样蛋白 (Aβ) 病理联系起来,这表明ACs是阿尔茨海默病 (AD) 的潜在早期生物标志物.
科学领域:
- 生物化学 生物化学
- 神经科学是一个神经科学.
- 代谢学 代谢学 代谢学
背景情况:
- 早期诊断阿尔茨海默病 (AD) 仍然是一个关键的挑战,阻碍了及时的治疗干预.
- 之前的研究表明了血化tau 181 (ptau181) 和血代谢产物,特别是中长链甲胺 (ACs) 之间的联系.
- 这种关联在粉样β负 (Aβ-) 和粉样β阳性 (Aβ+) 认知正常 (CN) 的老年人中都被观察到.
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