第一个三个月的部断裂与异常妊娠结果的关联
Yuping Duan1, Daoning Guo1, Dan Huang2
1Department of Ultrasonography, Mianyang Central Hospital, Mianyang, Sichuan, China.
Ultrasound quarterly
|December 16, 2024
概括
在头三个月内,部隔离 (NSs) 显著增加异常妊娠结果的风险. 患有NSs的患者面临的风险较高,与单独增加后透光度 (NT) 的患者相比.
科学领域:
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 产前诊断 在产前诊断
- 产科 产科 产科 产科 产科
背景情况:
- 增加的后半透明度 (NT) 和后隔膜 (NSs) 是第一季度的超声波标记.
- 这些标志物与不良妊娠结果有关,但它们的比较风险尚未完全阐明.
研究的目的:
- 为了比较胎儿怀孕异常结局的风险,部隔离 (NSs) 与增加的部透光 (NT) 厚度相比.
- 评估NSs与不良妊娠结果的独立关联.
主要方法:
- 从2018年1月到2020年12月,对311名NT≥3毫米或NSs患者进行了回顾性研究.
- 患者被分为三个组:NT 3-5毫米,NT >5毫米和NSs.
- 多变量逻辑回归分析,以评估异常妊娠结果的风险.
主要成果:
- 在NS组中,异常妊娠结果发生率最高 (92.0%),明显高于NT 3-5毫米组 (57.3%) 和NT>5毫米组 (75.2%).
- 对NS的超声波证据独立地与异常妊娠结果的显著更高风险相关 (OR = 8.552对于NT 3-5毫米;OR = 3.636对于NT>5毫米).
- 即使在为NT作为连续混因子进行调整后,NS仍然是一个重要的风险因素 (OR = 4.820).
结论:
- 在头三个月内出现隔膜 (NSs) 是异常妊娠结果的强有力的,独立的预测指标.
- 与单独增加的下巴半透明度 (NT) 相比,NS 具有显著更高的不良结果风险.
- 在头三个月内检测到NSs需要密切监测和就怀孕风险进行咨询.
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