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Updated: Jun 5, 2025

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人类大脑的加速细胞类型特定的调控进化.

Dennis Joshy1,2, Gabriel Santpere3, Soojin V Yi2,4,5

  • 1Department of Mechanical Engineering, University of California, Santa Barbara, CA 93106.

Proceedings of the National Academy of Sciences of the United States of America
|December 16, 2024
PubMed
概括

人类大脑的进化加速了基因表达的变化,特别是在神经元等特定细胞类型中. 这种特定于细胞类型的调节进化驱动了人类独特的大脑功能.

关键词:
大脑的进化,大脑的演变.细胞的特异性人类进化人类的进化.监管演变的监管演变一个单细胞转录组的转录组.

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The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
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