化物剂量-反应和抗菌剂草药抗菌剂和 (纳米-) 酸对牙虫的影响:一个体外研究
Richard Johannes Wierichs1, Mowliharan Kuruparan1, Abinaya Ruthiraswaran1
1Department of Restorative, Preventive and Pediatric Dentistry, ZMK Bern, University of Bern, Bern, Switzerland.
Caries research
|December 16, 2024
概括
化物牙膏在预防根 кариес方面显示出剂量反应效应. 虽然一些无化物选择提供了温和的保护,但它们仍然导致表面损失,与化物处理不同.
科学领域:
- 牙科研究 牙科研究
- 牙损伤预防 牙损伤的预防
- 矿物化的组织诊断.
背景情况:
- 研究含有草药剂或纳米-亚帕的无化物牙膏在预防虫方面的有效性.
- 评估牙科护理产品中的化物替代剂.
研究的目的:
- 评估各种无化物牙膏与含化物牙膏的牙预防作用.
- 为了确定化物的剂量反应关系,以防止脱矿化.
主要方法:
- 牛牙样本经历了28天的pH循环,使用不同的牙膏处理 (0-1100ppm化物,草药剂,纳米酸).
- 治疗包括用无化物 (NaF0),化物 (NaF500,NaF1100),葡萄种子提取物 (GSE),纳米-酸, melaleuca 油和 + 的牙膏进行刷牙.
- 综合矿物损失 (∆∆Z) 和损伤深度 (∆LD) 用横向微辐射学测量.
主要成果:
- 对于声音 (ST) 和非矿物化 (DT) 牙均观察到强烈的化物剂量反应.
- 只有NaF1100和GSE与去矿化牙 (DT) 的NaF0相比显示出显著差异.
- 化物 (NaF1100,NaF500) 是必要的,以防止表面损失,并在DT和ST上实现超矿化.
结论:
- 在这个pH循环模型中确立了化物度的明确剂量反应关系.
- 含有葡萄提取物或 melaleuca 油的无化牙膏在抑制根的进展方面表现出一定效果.
- 所有测试的无化物牙膏都导致了可观察的表面损失,与含的配方不同.
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