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基于的生物功能金属生物材料:探索它们的物理力学特性,生物意义和植入物应用
Ziyuan Liu1, Ming-Chun Zhao2, Dengfeng Yin2
1College of Mechanical Engineering, University of South China, Hengyang 421001, PR China; School of Materials Science and Engineering, Central South University, Changsha 410083, PR China.
Acta biomaterialia
|December 16, 2024
概括
基于 (Nb) 的金属生物材料由于其出色的机械和生物特性,对植入物具有很大的前景. 本综述详细介绍了它们的进展,优势和生物医学应用的未来前景.
科学领域:
- 生物材料科学 生物材料科学
- 材料工程 材料工程 材料工程
- 生物医学工程 生物医学工程
背景情况:
- 基于 (Nb) 的金属材料具有有利的物理机械和生物特性,使其适合植入物应用.
- 最近的进展集中在增强Nb基材料的生物功能,用于各种生物医学用途.
- 对用于植入物应用的基于Nb的生物材料进行全面审查的需求越来越大.
研究的目的:
- 在过去二十年中,为植入物应用提供了纯和基于Nb的金属材料的进展的全面概述.
- 突出基于Nb的金属生物材料的优点,包括它们的机械性能,耐腐蚀性,MRI兼容性和生物性能.
- 介绍基于Nb的金属生物材料的各种生产和加工技术,并讨论它们的植入应用.
主要方法:
- 过去20年来科学出版物的文献综述,重点是和基于Nb的金属生物材料.
- 分析生产和加工技术,如真空弧再,增材制造 (SLM,EBM),火花等离子烧结 (SPS) 和严重的塑料变形 (ECAP,MAF,HPT).
- 评估基于Nb的生物材料的物理力学特性,耐腐蚀性,MRI兼容性,细胞和血液兼容性,骨质生成和生物活性.
主要成果:
- 基于Nb的金属生物材料具有卓越的物理机械性能,在生物环境中具有出色的耐腐蚀性和良好的生物相容性.
- 这些材料对骨质生成和生物活性产生了积极影响,这对于骨再生和植入物集成至关重要.
- 不同的制造技术,包括增材制造和严重的塑料变形,为特定的植入物应用提供量身定制的特性.
结论:
- 基于Nb的金属生物材料非常适合各种植入物应用,因为它们具有平衡的特性.
- 对生产,加工和理解它们的生物相互作用的持续研究将进一步优化它们在生物医学设备中的使用.
- 未来的前景包括应对挑战,以充分实现Nb基生物材料在再生医学及其他领域的潜力.
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