[中国高血压患者的认知功能状态及其与血压控制的相关性]
1National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing100037, China.
Zhonghua xin xue guan bing za zhi
|December 16, 2024
概括
认知障碍影响了十分之一的中国高血压患者,患有高心血管风险. 尽管记忆力和视觉空间功能的认知能力显著下降,但认知状态在本研究中没有影响血压控制.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 高血压是心血管疾病和认知能力下降的主要危险因素.
- 了解高风险高血压患者的认知功能对于综合管理至关重要.
- 该ESPRIT研究为研究这种关系在中国提供了有价值的数据集.
研究的目的:
- 评估高心血管风险的中国高血压患者的全球和特定领域的认知功能.
- 为了确定这个人群中认知障碍和认知衰退的患病率.
- 探索认知功能与血压控制之间的关联.
主要方法:
- 采用ESPRIT研究 (2019年9月 - 2020年7月) 的数据进行的跨部门调查.
- 迷你精神状态检查 (MMSE) 用于评估认知功能,并将患者分为认知完整,认知下降和认知受损的群体.
- 使用多变量逻辑回归和灵敏度分析来评估认知功能对血压控制的影响.
主要成果:
- 分析了10834名高心血管风险高的高血压患者.
- 10.8%的患者表现出认知障碍,其中回忆记忆,视觉空间功能和注意力/计算能力受到影响最大.
- 80.1%的人表现出认知能力下降,主要是回忆记忆和视觉空间结构;认知功能与血压控制没有明显的相关性.
结论:
- 大约10%的高风险高血压患者有认知障碍,记忆和视觉空间功能等特定领域是最脆弱的.
- 这些患者中有很大一部分的认知能力下降,低于功能障碍的门.
- 认知功能,包括MMSE得分,在这个队列中没有被发现是血压控制的独立预测因素.
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