用植物疗法纠正肺炎中对目标器官的缺氧作用
Alla Philippova1, Raisa Aringazina2, Roberto Lozano3
1Department of Biology and General Genetics, I. M. Sechenov First Moscow State Medical University, Moscow, Russia.
Journal of complementary & integrative medicine
|December 16, 2024
概括
人参的成分,如切丁,改善了肺炎患者的ATPase总活性. 这表明植物制剂对治疗肺炎和改善组织氧化有希望.
科学领域:
- 植物疗法的分子机制
- 对呼吸道疾病的药理干预措施.
背景情况:
- 病毒性和细菌性肺炎的发病率不断增加,需要新的治疗策略.
- 组织缺氧是肺炎的关键并发症,需要改进管理.
研究的目的:
- 为了研究恒星素,氨酸和kaempferol (金生成分) 在治疗肺炎引起的组织缺氧的分子机制.
- 评估Panax植物制剂作为肺炎辅助治疗的疗效.
主要方法:
- 网络药理学方法在单中心研究中应用.
- 110名肺炎患者被分为安慰剂和Panax植物制剂组.
- 在2个月的时间内评估了物理 (肺功能,氧和) 和生化 (ATPase活性,葡萄糖,白细胞) 参数.
主要成果:
- 在肺炎患者中,服用凯姆菲罗尔,斯泰拉斯特林和奎尔塞丁显著增加了ATPase总活性.
- 与基线和安慰剂组相比,植物制剂组显示出增强的ATPase总活性.
- 植物制剂在控制与肺炎和缺氧相关的炎症反应方面表现出潜力.
结论:
- 人参成分在增强肺炎患者的细胞能量代谢 (总ATPase活性) 中表现有前途.
- 植物制剂是有效的辅助疗法,用于治疗肺炎,并改善缺氧患者的治疗结果.
- 对肺炎和缺氧的新型治疗策略进行进一步的研究是有必要的.
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