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相关概念视频

Allergic Reactions02:06

Allergic Reactions

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Antibody Structure01:10

Antibody Structure

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Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
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Allergic Drug Reactions01:27

Allergic Drug Reactions

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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Hypersensitivities01:30

Hypersensitivities

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
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Cross-reactivity00:42

Cross-reactivity

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过敏原免疫疗法免疫疗法

Jean-Nicolas Boursiquot1, Rémi Gagnon2, Jaclyn Quirt3

  • 1Division of Allergy and Clinical Immunology, Department of Medicine, Centre Hospitalier Universitaire de Québec, Université Laval, Québec, Québec, Canada. jnbou7@ulaval.ca.

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PubMed
概括
此摘要是机器生成的。

过敏原免疫疗法 (AIT) 为过敏性鼻炎,喘和昆虫过敏症提供疾病修饰. 决策需要全面的患者评估,风险与益处的讨论,以及由于过敏反应风险的医疗监督.

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科学领域:

  • 免疫学 免疫学 免疫学
  • 过敏和临床免疫学

背景情况:

  • 过敏原免疫疗法 (AIT) 是对过敏性鼻炎,过敏性喘和刺昆虫过敏的有效治疗方法.
  • 对AIT患者的选择涉及全面的评估,包括过敏测试和讨论目标,风险,益处和承诺.
  • 诸如症状严重程度,药物使用和患者偏好等因素影响过敏性鼻炎和喘中AIT的决定.

研究的目的:

  • 审查AIT的指示,禁忌和患者选择标准.
  • 详细说明AIT对食品以外的过敏原的使用,安全性和有效性.
  • 为医生提供关于处方和管理AIT的指导.

主要方法:

  • 目前关于过敏原免疫治疗的文献和临床指南的审查.
  • 在过敏性鼻炎和喘患者中影响AIT决策的因素分析.
  • 在AIT期间讨论安全协议和过敏反应的管理.

主要成果:

  • AIT是一种潜在的疾病修饰疗法,用于特定的过敏状况.
  • 仔细的患者选择和彻底的讨论对于成功的AIT至关重要.
  • 由于存在过敏反应的风险,AIT的使用,特别是皮下免疫疗法,需要医疗监督.

结论:

  • 过敏原免疫疗法是一个有价值的治疗选择,当指示和管理正确时.
  • 医生培训和适当的临床环境对于安全的AIT至关重要.
  • 本综述侧重于非食品过敏原的AIT,与食品免疫疗法分别讨论.