计算机断层扫描研究结果对于预测软组织肉瘤等级的有用性
Jeongyun Jeong1, Myounghun Kim1, Jongwon Koo1
1Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
概括
计算机断层扫描 (CT) 可以帮助预测狗的软组织肉瘤 (STS) 等级. 在CT扫描中,较大的瘤大小,异常的血管,脂肪浅和淋巴腺病与较高的STS等级相关.
科学领域:
- 兽医辐射学 兽医辐射学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 软组织肉瘤 (STSs) 是源于介质细胞的多种瘤.
- 精确的STS分期对于治疗规划和预测结果至关重要.
- 组织学分级显著影响STS复发和转移,但通过成像仍然具有挑战性的术前分级.
研究的目的:
- 调查计算机断层扫描 (CT) 发现是否可以区分狗软组织肉瘤 (STS) 的组织学等级.
- 识别与不同STS等级 (1,2,3) 相关的特定CT成像特征.
主要方法:
- 追溯分析了30只经过基因病理学确认的STS (12级1,10级2,8级3) 的狗的CT扫描.
- 评估各种CT特征:瘤划分,血管性,增强模式,化,囊性病变,脂肪,淋巴腺病变和肺转移.
- 瘤大小和衰减值的定量评估 (对比前后).
主要成果:
- 在STS等级之间观察到瘤大小的显著差异,瘤内/瘤周围血管的异形,瘤周围脂肪串流,以及转移性区域淋巴腺病.
- 3级STS较大,与1级相比,异形血管的患病率更高.
- 3级STS患者的相邻转移性淋巴腺病发病率明显高于2级STS患者.
结论:
- CT成像特征,包括瘤大小和血管性,可以帮助区分软组织肉瘤在狗中的组织学等级.
- 在基因组病理学前确定这些CT特征可能有助于规划STS的外科切除边缘.
- 进一步的研究可以完善基于CT的分级,以改善兽医瘤学中的STS管理.
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