确定美国退伍军人的跨诊断性创伤性压力反应:一项全国代表性的研究
Cameron P Pugach1, Shane W Adams2,3, Blair E Wisco1
1Department of Psychology, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.
Journal of traumatic stress
|December 17, 2024
概括
这项研究在美国退伍军人中确定了五个不同的创伤性压力反应 (TSR),揭示了不同的弹性水平和功能结果. 了解这些表型有助于个性化治疗创伤后应激障碍 (PTSD) 和相关疾病.
科学领域:
- 精神病学和行为健康
- 流行病学 流行病学
- 临床心理学 临床心理学
背景情况:
- 创伤性压力反应 (TSRs) 涵盖了从恢复力到创伤后应激障碍 (PTSD) 和并发性疾病的范围.
- 需要全面的方法来理解TSR在不同人群中的异质性.
- 美国军方退伍军人代表着一个大量暴露于创伤和潜在的各种压力反应的人群.
研究的目的:
- 在美国退伍军人的全国代表性样本中描述TSR的临床表型.
- 通过跨诊断和多维方法识别TSR的离散隐性类别.
- 检查已识别的TSR类的人口,军事,创伤和心理社会相关性.
主要方法:
- 使用了从国家健康和退伍军人恢复力研究中从3727名美国退伍军人的横截面数据中中出方法.
- 采用隐性类别分析来识别基于自我报告的PTSD,普遍焦虑,抑郁症状和功能上的不同群体.
- 分析了所识别的阶级与人口,军事,创伤和心理社会变量之间的关联.
主要成果:
- 确定了五种潜在类别:低TSR (61.3%),焦虑/抑郁 (16.6%),避免性兴奋 (9.2%),失调性兴奋 (8.2%) 和高TSR (4.7%).
- 患有失调性兴奋和高TSR类的退伍军人表现出显著下降的功能.
- 课程区分了对PTSD症状的弹性与所有领域的弹性;与人口统计学,军事,创伤和心理社会因素发现的关联.
结论:
- 退伍军人表现出TSR的独特临床表型,这表明潜在的信息病因学,诊断亚型和个性化治疗策略.
- 虽然大多数患有精神病理的退伍军人经历了功能障碍,但有一个显著的子集尽管有症状,但仍然保持着高功能.
- 研究结果强调了多维方法的重要性,以了解和解决创伤性压力对退伍军人的多种影响.
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