在COVID-19期间肺癌检测的中断
Trisha Lal1,2,3, Uriel Kim2,3,4,5, Christina S Boutros1,2,6
1Division of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Cancers
|December 17, 2024
概括
由于COVID-19大流行,肺癌的检测显著减少,农村和少数民族人口的差异显著. 恢复是部分的,强调需要有针对性的干预措施来解决这些持续存在的差距.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 全球范围内,COVID-19大流行影响了医疗保健的获取和提供.
- 癌症查和诊断的中断可能导致检测延迟,结果更差.
研究的目的:
- 量化COVID-19大流行对肺癌检测率的影响.
- 在疫情期间,检查肺癌诊断在人口和社区因素之间的差异.
- 评估肺癌检测在流行病的前两年恢复的情况.
主要方法:
- 使用监测,流行病学和最终结果 (SEER) 数据库 (2001-2021) 的回顾性队列研究.
- 基于使用Joinpoint回归的流行前趋势 (2000-2019) 的2020-2021年预期肺癌发病率.
- 计算了预期和观察到的发病率之间的百分比差异;对转移性疾病诊断几率进行了多变量和倾向性得分分析.
主要成果:
- 与预测相比,肺癌发病率在2020年下降了10%,不成比例地影响农村人口,非西班牙裔黑人和亚洲患者以及女性.
- 到2021年,检测率部分恢复,但仍低于预期水平5%,局部疾病检测有所改善.
- 农村,非大都市社区经历了进一步的下降;小细胞肺癌 (SCLC) 患者和少数民族群体在2021年期间表现出持续较高的远程疾病呈现率.
结论:
- 疫情导致肺癌检测显著减少,到2021年恢复不完全.
- 在检测和诊断方面观察到持续的差异,特别是在农村和少数民族人口中.
- 有针对性的干预措施对于重新吸引服务不足的社区和减轻对肺癌结果的长期影响至关重要.
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