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Updated: Jun 4, 2025

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
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Published on: January 7, 2019

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TRPC1的lysines对异构TRPC5-TRPC1通道功能的影响

Isaac S Demaree1, Sanjay Kumar1,2, Kayla Tennessen3

  • 1Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Cells
|December 17, 2024
PubMed
概括

TRPC1通过孔膜中特定的带正电荷的氨酸残留物抑制TRPC5离子通道功能. 这一发现澄清了TRPC5/TRPC1异构体调节和细胞外Mg2+抑制的机制.

关键词:
在 TRPC 频道上.TRPC1-TRPC5异构体中的一个.电离通道的电离通道.电力生理学 电力生理学分子动力学分子动力学

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