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地中海饮食中的关键营养素及其对炎症性肠病的影响:叙述性综述

Sara Deleu^1,2, Guia Becherucci², Lihi Godny³

¹CEMAD Translational Research Laboratories, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.

|December 17, 2024

概括

地中海饮食可以通过积极影响肠道微生物群来帮助管理炎症性肠道疾病 (IBD). 这种饮食中的特定营养在IBD的临床前研究中显示出有希望,但需要更多的临床研究.

科学领域:

胃肠病学胃肠病学
营养科学营养科学
微生物学微生物学

背景情况:

肠道微生物组在炎症性肠道疾病 (IBD) 的发展和进展中发挥着关键作用.
饮食干预被认为是调节IBD管理中的肠道微生物群的有希望的策略.
地中海饮食,以高摄入植物性食品和健康脂肪为特征,与降低慢性疾病风险有关,包括IBD.

研究的目的:

审查地中海饮食中丰富的特定营养素及其对IBD的影响.
专注于关于这些营养素对IBD的影响的临床前证据.
突出进一步临床研究的必要性,以了解IBD中的特定营养素机制.

主要方法:

文献综述侧重于地中海饮食成分和IBD的临床前研究.
关于地中海饮食成分的科学文献分析.
综合有关特定营养素对肠道微生物群和IBD模型影响的证据.

主要成果:

在地中海饮食中发现的几种营养素,包括果糖-寡糖,奇托,植物性蛋白质,多,欧米茄-3多不和脂肪酸和白醇,在临床前IBD模型中显示出潜在的益处.
这些营养素会影响肠道微生物群的组成和功能.
支持这些发现的临床证据往往有限.

结论:

地中海饮食提供了一种有希望的,较少限制的饮食方法,用于IBD管理,因为它的营养成分.
地中海饮食中的特定营养物质需要进一步研究它们在IBD中的治疗潜力.
进一步的研究是必不可少的,以建立基于营养特异性相互作用的IBD管理的个性化,多学科的方法.

关键词:

IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD 地中海饮食地中海饮食炎症性肠病是一种炎症性肠病.营养素营养素营养素

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