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Updated: Jun 4, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

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综合性临床遗传学,分子和病理评估有效地协助诊断和治疗选择在乳腺癌患者与遗传遗传背景的患者

Petra Nagy1, János Papp1,2, Vince Kornél Grolmusz1,2

  • 1Department of Molecular Genetics and The National Tumour Biology Laboratory, National Institute of Oncology, Comprehensive Cancer Centre, Ráth György u. 7-9, 1122 Budapest, Hungary.

International journal of molecular sciences
|December 17, 2024
PubMed
概括

综合遗传性癌症基因组测试显著增加了在患有遗传性乳腺和卵巢癌 (HBOC) 综合征的患者中检测可采取行动的变异. 扩展测试发现了更多的致病变体,有助于个性化管理和治疗选择.

关键词:
没有NGS,没有NGS.乳腺癌 乳腺癌 乳腺癌诊断 诊断 诊断 诊断 诊断基因检测 基因检测是指基因检测.细菌线的生殖线这是一种遗传性遗传.多基因面板的组件.卵巢癌是发生在卵巢的癌症.

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