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Updated: May 6, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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短期暴露于非功能化聚乙烯纳米颗粒对人类外周血液单核细胞中DNA甲基化和基因表达的影响

Kinga Malinowska1, Kateryna Tarhonska2, Marek Foksiński3

  • 1Department of Biophysics of Environmental Pollution, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska Str. 141/143, 90-236 Lodz, Poland.

International journal of molecular sciences
|December 17, 2024
PubMed
概括

聚乙烯纳米颗粒 (PS-NPs) 没有改变全球DNA甲基化,但在高度下增加了5-基甲基-2'-脱氧氨. 较小的PS-NP (29nm,44nm) 调节TP53和CDKN2A基因表达,表明大小和度依赖的影响.

关键词:
表观遗传性DNA修饰是指DNA的修饰.周围血液中的单核细胞.聚乙烯纳米粒子聚乙烯纳米粒子它们是原始科基因.抑制基因的抑制基因

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