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Updated: Jun 4, 2025

Cell Type-specific Gene Expression Profiling in the Mouse Liver
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缺氧诱导因子-2α通过诱导肝细胞死亡促进肝纤维化

Raja Gopal Reddy Mooli1, Dhanunjay Mukhi1, Mikayla Watt1

  • 1Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

International journal of molecular sciences
|December 17, 2024
PubMed
概括

肝细胞中的缺氧诱导因子-2α (HIF-2α) 通过增加细胞死亡促进肝纤维化. 阻断肝细胞HIF-2α可以减少肝纤维化,并增强细胞生存途径.

关键词:
灭症 (apoptosis) 是一种死亡的过程.纤维化 纤维化肝细胞 肝细胞缺氧 缺氧是指缺氧的情况.缺氧诱导因子-2αα

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