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猪精液特征的基因组预测,包括生物相互作用
Yantong Chen1, Fang Yang1, Yanda Yang1
1Key Laboratory of Livestock and Poultry Resources (Pig) Evaluation and Utilization, Ministry of Agriculture and Rural Affair, Yuelushan Laboratory, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
International journal of molecular sciences
|December 17, 2024
概括
猪精液特征的基因组预测显示中等准确度. 纳入基因相互作用显著改善预测,特别是精子异常率,增强育种计划.
科学领域:
- 动物遗传学动物遗传学
- 生殖生物学 生殖生物学
- 量化遗传学 量化遗传学
背景情况:
- 现代养猪业严重依赖野猪遗传学进行人工授精.
- 之前的育种计划优先考虑生产特征而不是精液质量.
- 野猪精液的特征对于猪有效繁殖至关重要.
研究的目的:
- 为了估计猪精液关键特征的遗传参数.
- 评估这些特征的基因组预测准确性.
- 评估基因相互作用对预测准确性的影响.
主要方法:
- 来自2467只Duroc猪的274,332次射精的表型数据.
- 对精子异常率 (ABN),体积 (VOL),度 (DEN) 和运动率 (MOT) 的遗传性估计.
- 使用了基因组最佳线性无偏预测 (GBLUP) 和双基 GBLUP (biBLUP) 模型.
主要成果:
- 遗传概率估计在0.16 (MOT) 到0.43 (ABN) 之间.
- GBLUP实现了中等预测能力 (0.32-0.50).
- 通过将基因相互作用通过KEGG通路结合起来,biBLUP显著提高了预测准确性 (9.50%-20.10%).
结论:
- 杜罗克野猪的精液特征表现出中度到低的遗传性.
- 基因组预测为野猪精液特征提供了适度的准确性.
- 对基因相互作用的计算大大提高了对野猪生殖特征的基因组预测.
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