在低风险单胎怀孕中,与早期早产相关的孕产妇发病率
Moti Gulersen1, Erez Lenchner2, Alisha Goyal1
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Journal of clinical medicine
|December 17, 2024
概括
早期和极端早产增加了母亲的风险,包括输血,子宫破裂,子宫切除术和ICU入院. 这些发现强调了在早产期间对母亲的护理的关键考虑.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 公共卫生 公共卫生
背景情况:
- 早期早产的新生儿结果已经确立,但母亲的发病风险仍然不太了解.
- 调查与极端和早期早产相关的孕产妇并发症对于综合护理至关重要.
- 现有的研究往往忽视了早产对母亲健康的影响.
研究的目的:
- 评估早产早产与孕产妇疾病之间的关联.
- 量化在早产期出生的特定母亲并发症的风险,与到期的出生相比.
- 为临床实践提供有关早产产妇产妇风险的信息.
主要方法:
- 使用美国生育现场出生数据库 (2016-2021) 进行回顾性队列研究.
- 包括低风险单独怀孕,不包括高风险的情况.
- 在妊娠年龄组中对母亲病率的比较:极度早产 (23-27周),早期早产 (28-33周) 和终产 (37-41周).
- 多变量逻辑回归分析以调整混因素,呈现调整的几率比率 (aOR) 和95%置信区间 (CI).
主要成果:
- 对18.797.394名活产儿的分析显示了重要的关联.
- 极端和早期的早产与增加母体输血,子宫破裂,意外切除子宫和ICU入院的几率相关.
- 相反,在早产群体中,严重围破伤的几率较早,而在早产群体中,其几率较低.
结论:
- 早产和极度早产与新生儿问题之外的重大孕产妇疾病有关.
- 孕产妇的风险包括更高的输血概率,子宫破裂,子宫切除术和ICU入院.
- 这些发现强调了在管理早产时需要考虑母亲的并发症的必要性.
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