在没有动脉样硬化心血管疾病的老年患者中评估心血管风险
Witold Żurański1, Justyna Nowak2, Aleksander Danikiewicz3
1Third Department of Cardiology, Silesian Center for Heart Disease, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Journal of clinical medicine
|December 17, 2024
概括
大多数70岁以上的老年人面临高动脉样硬化心血管疾病 (ASCVD) 风险,通常超过值. 年龄和高血压是关键因素,除了营养不良和多药等常见问题之外.
科学领域:
- 老年学是一门学科.
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 年龄是动脉样硬化心血管疾病 (ASCVD) 的主要危险因素.
- 几乎所有70岁及以上的个人都超过了传统的10年ASCVD风险值.
- 在老年人中,ASCVD风险调整因子如营养不良,多药和并发症是关键考虑因素.
研究的目的:
- 在看似健康的老年人 (70岁以上) 中估计10年ASCVD风险.
- 用生物化学和临床指标来描述这一群体.
- 评估ASCVD风险修饰因子在这个人口群体中的流行程度.
主要方法:
- 这项研究招募了253名看似健康的老年人 (70岁以上),没有确定的ASCVD.
- 系统冠状动脉风险估计2-老年人 (SCORE2-OP) 模型被用于评估10年ASCVD风险.
- 生物化学和临床指标被评估以表征参与者.
主要成果:
- 16.2%的人有高风险,83.8%的人有非常高的ASCVD风险;没有参与者有低风险.
- 10年的中位数ASCVD风险为23%,随着年龄 (75岁以上) 的增加,风险显著增加.
- 年龄 (≥75岁) 与非常高的ASCVD风险密切相关 (C统计值0.92,PPV 99%,NPV 52%).
结论:
- 没有确定的ASCVD的老年人是一个异质的群体,大多数人面临非常高的风险.
- 年龄和高血压是该人口中ASCVD风险的主要因素.
- 营养不良,多药性和多病性是经常观察到的ASCVD风险修饰因素.
相关概念视频
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