影响急性胰腺炎开放性切除术死亡率的危险因素:比较分析
Tudorel Mihoc1, Catalin Pirvu1, Amadeus Dobrescu2
1Department X, Surgical Emergencies Clinic, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Romania, 300041 Timișoara, Romania.
Journal of clinical medicine
|December 17, 2024
概括
对急性胰腺炎的开放性瘤切除术具有很高的死亡率. 危险因素包括老年,器官衰竭和早期手术. 将手术推迟到28天以后显著提高了接受瘤切除术的患者的生存率.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
背景情况:
- 急性胰腺炎 (AP) 具有显著的发病率和死亡率风险.
- 开放性瘤切除术 (ON) 是严重AP的关键干预措施,但与高不良结果相关.
研究的目的:
- 为了确定在接受ON治疗AP的患者中死亡的风险因素.
- 为了比较ON的幸存者和非幸存者之间的结果.
主要方法:
- 追溯分析了74名为AP接受ON治疗的患者.
- 在幸存者和非幸存者组之间对手术前和术后变量的比较.
主要成果:
- 死亡率为29.73%的人.
- 死亡的重要风险因素包括年龄>60,多器官衰竭,早期ON (<28天),较高的中性粒细胞与淋巴细胞比率 (NLR),出血和肠.
- 延迟的ON (>28天) 的死亡率明显较低 (12.5%),而不是早期的ON (50%).
结论:
- 年龄,AP严重程度,ON时间和术后并发症显著影响ON死亡率.
- 延迟ON超过28天和优化手术技术对于改善患者的治疗结果至关重要.
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