对比L L聚乙烯甘醇加上亚酸和口服硫酸片用于结肠镜肠道制备
Jin Hwa Park1, Minjun Kim2, Seung Wook Hong2
1Department of Gastroenterology, University of Hanyang College of Medicine, 222-1, Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea.
低容量聚乙烯甘醇加上酸 (PEG-A) 和口服硫酸片 (OST) 是有效的结肠镜准备. OST表现出更好的耐受性,而PEG-A引起的腹部张张较少,两者对老年患者都是安全的.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 药理学 药理学是指药理学的学科.
背景情况:
- 结肠镜肠道制备的新药包括低容量 (1L) 聚乙烯甘醇加酸 (PEG-A) 和口服硫酸片 (OST).
- 评估这些药物的比较疗效,安全性和耐受性对于优化患者准备和结肠镜检查结果至关重要.
研究的目的:
- 为了比较1升PEG-A与OST用于结肠镜肠道准备的疗效,安全性和耐受性.
- 评估患者的满意度,并确定与每个制备方法相关的特定不良事件.
主要方法:
- 一个单中心,前性,随机的,内镜盲目的研究.
- 174名患者被随机分为两个组:1L PEG-A (n=92) 和OST (n=82).
- 使用波士顿肠道制备量表 (BBPS) 评估了肠道制备的有效性;通过问卷评估了耐受性和安全性.
主要成果:
- 两组的成功排便准备率都很高,而且相似 (PEG-A为91.3%,OST为95.1%,p=0.324).
- 与PEG-A相比,OST的整体患者满意度显著更高 (8.2比6.8,p < 0.001).
- 使用PEG-A时腹部张张的频率较低 (3.3%对11.0%,p=0.045),但整体不良事件相似 (29.3%对25.6%,p=0.583).
结论:
- 1L PEG-A 和 OST 都是有效,安全和耐受良好的肠道制备选项,用于结肠镜.
- OST表现出优异的患者耐受性和满意度,而PEG-A与较少的腹部膨胀有关.
- 这两种药物在老年患者 (≥65岁) 的小组中都被证明是有效和安全的.
更多相关视频
08:53Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
Published on: July 27, 2022
08:58Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
Published on: January 5, 2017
相关概念视频
Drugs Affecting GI Tract Motility: Other Laxatives
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures II: Colonoscopy
Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This...
Drugs for Treatment of Ulcerative Colitis in IBD
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
