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Updated: Jun 4, 2025

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head
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Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

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指-E-box-binding homeobox-1的减少可以通过Wnt/β-catenin通路抑制H型血管形成,从而加速大腿骨头的类固醇诱导骨硬化

Guangyang Zhang1, Yuanqing Cai1, Jialin Liang1

  • 1Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Animal models and experimental medicine
|December 17, 2024
PubMed
概括

指-E-box-binding homeobox-1 (ZEB1) 减少会损害H型血管,导致类固醇诱导的股骨头骨硬化 (SONFH) 的血管生成和骨质生成减少. 激活Wnt/β-catenin通路可以改善这些过程.

关键词:
在Wnt/β-catenin路径中.股骨头的类固醇诱导的骨髓缩.类型-H船只的船只.指 E 盒绑定 家庭盒-1 盒-1

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