将α-烯酸转化为n-3长链多不和脂肪酸:生物可用性和饮食调节
Lei Wang1, Chen Cheng1, Xiao Yu1,2
1Hubei Key Laboratory of Lipid Chemistry and Nutrition, and Key Laboratory of Oilseeds Processing, Ministry of Agriculture, Oil crops and Lipids Process Technology National & Local Joint Engineering Laboratory, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, Hubei, China.
Critical reviews in food science and nutrition
|December 17, 2024
概括
饮食中的α-烯酸 (ALA) 可以增加必需的omega-3,但其转化效率低下. 用特定营养物质优化ALA的输送可能会增强健康益处并提高转化率.
科学领域:
- 营养生物化学 营养生物化学
- 代谢调节 代谢调节 代谢调节 代谢调节
- 食中的脂肪酸 食中的脂肪酸
背景情况:
- N-3长链多不和脂肪酸 (n-3 LCPUFA) 对健康至关重要,但在全球范围内消耗不足.
- 植物衍生的α-烯酸 (ALA) 提供了n-3 LCPUFA丰富的潜力,但面临的代谢挑战,如低转化效率和高氧化.
研究的目的:
- 审查ALA的代谢命运,从摄入到肝脏处理.
- 探索监管目标和影响ALA转化为有益的n-3 LCPUFA的因素.
- 提出一种关于影响ALA转换的"快速"或"缓慢"代谢途径的假设.
主要方法:
- 文献综述侧重于含有ALA的脂质的吸收,运输和代谢.
- 在体内分析影响ALA转化效率的因素.
- 讨论潜在的饮食干预措施来增强ALA代谢.
主要成果:
- ALA 转化为 n-3 LCPUFA 是一个复杂的过程,受吸收,运输和肝脏代谢的影响.
- 饮食成分包括结构性脂质,脂质,碳水化合物,蛋白质,氨基酸,多,维生素和矿物质差异调节ALA转化.
- 为ALA的代谢过程提出了一个"快速"或"缓慢"的模型.
结论:
- 改善ALA的代谢转化是利用其健康益处的关键.
- 涉及量身定制的ALA输送系统和联合管理营养素或植物化学品的协同效应策略是有希望的.
- 未来的研究应该专注于精确的输送和营养组合,以优化ALA的利用.
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