在R1-pS262陶氏诱导的内源性陶氏聚合,突触损伤和认知障碍中,对R1-pS262陶氏的构造模式发生了变化

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In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein

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Gang Wu1,2, Yong Luo1,2, Qian Guo1

  • 1School of Basic Medicine, Key Laboratory of Education Ministry/Hubei province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Journal of Alzheimer's disease : JAD
|December 17, 2024
PubMed
概括

在Ser262的陶酸化驱动蛋白质聚合和神经退行在阿尔茨海默氏症 (AD). 这一发现为陶病和潜在的治疗点提供了新的见解.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.R1-pS262 的意思是酸化的方法是:光化.蛋白质折叠的形状代码是蛋白质的折叠.图的聚合方式是tau.

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