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Updated: Jun 4, 2025

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ATAD2和TWIST1的相互作用促进了MYC在结肠直肠癌中的激活

Anirban Roy1, Babu Sudhamalla1

  • 1Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741246, India.

Biochemistry
|December 17, 2024
PubMed
概括

ATPase家族AAA域含有蛋白2 (ATAD2) 和TWIST1相互作用激活MYC,推动结肠癌细胞的增殖和生存率低下. 这个ATAD2-TWIST1-MYC轴是一个潜在的治疗目标.

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