相关实验视频

Updated: May 13, 2026

$Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus$

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus

Published on: January 23, 2018

在肌肉骨疾病的治疗中,内脂肪衍生非细胞产品:一个范围审查

Aditya Fuad Robby Triangga^1,2,3, Widya Asmara⁴, Rahadyan Magetsari^1,3

¹Department of Orthopaedics and Traumatology, RSUP Dr. Sardjito, Yogyakarta, Indonesia.

Orthopedic reviews

|December 17, 2024

概括

研究人员探索了用于肌肉骨疾病的创新治疗方法,使用皮下脂肪 (IPFP) 作为干细胞衍生的非细胞产品的来源. 这些IPFP衍生生物在减少炎症和促进骨科疾病的组织再生方面表现有前途.

科学领域:

再生医学是一种再生医学.
整形外科整形外科整形外科
生物技术是生物技术.

背景情况:

肌肉骨疾病带来复杂的挑战,治疗选择有限.
来自干细胞的非细胞产品正在成为创新的治疗解决方案.
皮下脂肪 (IPFP) 越来越被认为是中细胞干细胞 (MSC) 衍生的非细胞产品的来源.

研究的目的:

审查IPFP衍生细胞生物制剂在治疗骨科疾病方面的进展.
专注于用于骨关节炎和带/肌损伤的应用.
确定IPFP衍生非细胞产品用于肌肉骨疾病的使用方面的进展.

主要方法:

在PubMed,Scopus和谷歌学者中进行了全面的文献搜索.
审查的重点是过去10年内发表的研究.
为了对IPFP的细胞间信使信号分子 (外体,秘密体,条件介质) 的范围审查,遵循了PRISMA-ScR指南.

主要成果:

六项研究符合审查的纳入标准.
来自IPFP的非细胞产品在肌肉骨疾病中表现出显著的抗炎作用.
观察到的效应包括微观的细胞和矩阵变化,以及对炎症标志物和基因表达的定量分析.

结论:

来自IPFP的非细胞产品显示出在肌肉骨疾病中再生疗法的巨大潜力.
这些药物有效降低炎症,促进细胞和组织的再生.
进一步的研究是必不可少的,以充分阐明这些生物制剂的特性和治疗应用.

关键词:

条件化介质是指一个条件化介质.外基因组是外基因组中的一个.皮下脂肪子的脂肪子肌肉骨疾病的疾病一些秘密一些秘密.

更多相关视频

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Published on: September 29, 2018

Isolation, Expansion, and Differentiation of Mesenchymal Stem Cells from the Infrapatellar Fat Pad of the Goat Stifle Joint

Isolation, Expansion, and Differentiation of Mesenchymal Stem Cells from the Infrapatellar Fat Pad of the Goat Stifle Joint

Published on: August 2, 2022

相关概念视频

Connective Tissue Cell Types

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...