微观失眠. 微观失眠. 一个重新评估
JAMA
|February 8, 1985
概括
在两个患者群体中,微度昏迷的表现不同. 老年人,通常是患有多种疾病和正静性低血压的女性,代表了一个更大,以前被描述不足的群体.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 老年病的医生 老年病的医生
背景情况:
- 排尿失眠 (MS) 是一种与排尿相关的暂时意识丧失.
- 虽然年轻,健康的男性的多发性硬化病记录得很好,但对其他患者群体的了解较少.
研究的目的:
- 在多样化的患者队列中调查吐失眠的特征和临床表现.
- 确定患有多发性硬化症的不同患者群体及其相关风险因素.
主要方法:
- 对33名被诊断患有排尿失眠的患者进行前性研究.
- 收集患者数据包括年龄,性别,并发症,药物和体检结果 (特别是静止性低血压).
- 对复发性昏迷或不良事件的后续评估,平均为15.3个月.
主要成果:
- 确定了两个不同的组:8名年轻,健康的男性 (平均年龄25岁) 评估正常,和25名老年患者 (平均年龄60岁),主要是女性 (16/25).
- 年龄较大的群体表现出更高的疾病负担,平均每名患者患上3.8种并发病和3.5种药物.
- 在25名老年患者中,22名患者检测到正静性低血压,并开始针对正静性的治疗.
- 在随访期间,在整个研究队列中没有观察到复发性排尿失眠或突然死亡.
结论:
- 微观昏迷可以分为两个主要组:年轻的健康男性和较大的老年人群,通常是女性.
- 患有多发性硬化症的老年患者经常出现多种并发性疾病和高患病率的正静性低血压.
- 专注于改善静止功能的管理策略似乎有效地预防这种人群的复发性昏迷和不良结果.
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