在现实世界中,无法控制喘的预测参数:一项前性研究
Sibel Ayik1, Gülistan Karadeniz2, Tamay Tatlı2
1Division of Pulmonary, Allergy and Critical Care Medicine, Izmir Katip Çelebi University Atatürk Educatıon And Research Hospıtal, İzmir, Turkey.
概括
超过一半的喘患者患有无法控制的喘,女性性别,肺功能不佳和非MART治疗是关键预测因素. 改善药物坚持对于更好的喘控制至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 临床医学 临床医学
- 呼吸系统健康 呼吸系统健康
背景情况:
- 喘管理的目标是完全控制,但不受控制的病例正在增加.
- 识别导致失控喘的因素对于有效的患者护理至关重要.
研究的目的:
- 确定不受控制的喘的患病率.
- 识别出失控喘的预测因素.
- 将单次维持和缓解疗法 (MART) 与非MART治疗方案进行比较.
主要方法:
- 对495名喘患者进行了前性调查问卷.
- 喘控制测试 (ACT) 用于将患者分类为受控和不受控制的组.
- 莫里斯基药物坚持度表 (MMAS) 评估了治疗的坚持.
主要成果:
- 54.9%的患者患有无法控制的喘.
- 预测因素包括女性性别,低FEV1/FVC%,最近的急诊室访问和非MART治疗.
- 没有控制的喘患者表现出较低的药物坚持 (较高的MMAS得分).
- 与非MART组 (61.2%) 相比,MART组的非控制性喘发生率较低 (43.8%).
结论:
- 失控喘的危险因素包括女性性别,急诊,住院,肺功能差,粘附性低,非MART治疗.
- 与非MART治疗相比,MART治疗方案显示出更好的喘控制.
- 解决诸如坚持和治疗类型之类的预测因素是改善喘控制的关键.
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