NABP-BERT:基于来自变压器 (BERT) 架构的双向编码器表示的NANOBODY®抗原结合预测

相关实验视频

Updated: Jun 4, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
06:50

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

1.7K

Fatma S Ahmed1,2, Saleh Aly3, Xiangrong Liu1

  • 1Department of Computer Science and Technology, Xiamen University, Xiamen 361005, China.

Briefings in bioinformatics
|December 17, 2024
PubMed
概括

使用序列数据,NABP-BERT预测了纳米体与抗原的结合. 这种深度学习模型通过克服实验识别的局限性来加速纳米体 (Nbs) 的开发,用于各种应用.

关键词:
贝尔特 (BERT) 公司纳米人体 (NANOBODY®) 是一种抗原是一种抗原.有约束力的预测预测.深度学习是一种深度学习.序列嵌入方式 序列嵌入方式

更多相关视频

Validation of Nanobody and Antibody Based In Vivo Tumor Xenograft NIRF-imaging Experiments in Mice Using Ex Vivo Flow Cytometry and Microscopy08:09

Validation of Nanobody and Antibody Based In Vivo Tumor Xenograft NIRF-imaging Experiments in Mice Using Ex Vivo Flow Cytometry and Microscopy

Published on: April 6, 2015

11.6K
Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology09:12

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

Published on: May 3, 2021

2.5K

相关概念视频

Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
4.2K