2型糖尿病与神经感官听力损失的关联 - 一个基于人口的分析分析
Marwin Li1, Natalie M Perlov1, Jena Patel2
1Sidney Kimmel Medical College, Thomas Jefferson University, USA.
Neuro endocrinology letters
|December 17, 2024
概括
2型糖尿病患者有较高的感觉神经听力损失 (SNHL) 风险. 控制不良的糖尿病 (较高的HbA1c) 和年龄较大显著增加了SNHL风险,这表明需要进行听力测试查.
科学领域:
- 内分泌学 在内分泌学.
- 听力学 听力学是指听力学.
- 流行病学 流行病学
背景情况:
- 2型糖尿病是一种普遍的慢性疾病,影响全球数百万人.
- 新出现的证据表明,糖尿病和听力障碍之间存在潜在联系.
- 感官神经听力损失 (SNHL) 是导致残疾的重要原因,影响沟通和生活质量.
研究的目的:
- 调查2型糖尿病与感觉神经听力损失 (SNHL) 的风险之间的关联.
- 确定血糖控制 (HbA1c水平) 和患者年龄是否会改变这种风险.
- 为了比较糖尿病患者和非糖尿病对照患者的SNHL发病率.
主要方法:
- 一个回顾性队列研究利用TrinetX美国协作网络 (2003-2022).
- 分析了被诊断为2型糖尿病的患者的电子病历,根据HbA1c水平 (8.0-13.9%或≥14.0%) 和诊断时的年龄分层.
- 倾向性得分匹配用于控制混因素,比较糖尿病人群与年龄匹配的非糖尿病人群.
主要成果:
- 与非糖尿病对照组相比,糖尿病患者的SNHL风险显著增加.
- 较高的HbA1c水平 (≥14.0%) 与大多数年龄组的SNHL风险增加有关,除了最年轻的队列 (21-40岁).
- 老年患者 (在诊断时≥71岁) 患SNHL风险最高,特别是那些糖尿病控制不良 (HbA1c≥14.0%) 患者.
结论:
- 2型糖尿病的诊断与患SNHL的风险增加密切相关.
- 这种风险在老年人和低于最佳血糖控制的人群中尤为明显.
- 对于患有2型糖尿病的患者,特别是老年人,应考虑进行例行听力检查.
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