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Updated: Jun 4, 2025

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阿波脂蛋白和外围动脉疾病:孟德尔的随机化分析分析

Chen-Xin Wan1, Yu-Shu Gong2, Tao Xu3

  • 1Pu'ai Hospital, Huazhong University of Science and Technology, Tongji Medical College, Wuhan City, China.

Vascular
|December 17, 2024
PubMed
概括

升高的阿波利波蛋白B/A1比率显著增加了周围动脉疾病 (PAD) 的风险. 高血压,心肌梗塞和缺血性中风调解了这种关联,解释了81%的因果关系.

关键词:
周围动脉疾病 周围动脉疾病这是一种Apolipoprotein蛋白.调解 调解 是一种调解方式.门德尔的随机化是门德尔的随机化

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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