摄入超吸收聚合物 ("水珠"):一个中毒中心研究的结果
Catherine Dong1, Oyeyimika Oyekanmi1, Zach Deuell1
1Department of Emergency Medicine, Division of Clinical Toxicology, Virginia Commonwealth University Health System, Richmond, VA, USA.
摄入超吸收聚合物 (SAP),通常来自水珠,很少导致儿童的肠道阻塞. 这项研究在分析的病例中没有发现任何障碍或严重的结果,这表明严重并发症的发生率很低.
科学领域:
- 毒理学 毒理学 毒理学
- 儿科胃肠病学 儿科胃肠病学
- 材料科学 材料科学 材料科学
背景情况:
- 超吸收性聚合物 (SAP) 是水友性材料,在水中显著膨胀.
- 幼儿摄入"水珠" (SAP) 引发了对潜在的肠道阻塞的担忧.
- 摄入SAP后肠道阻塞的实际发病率尚不清楚.
研究的目的:
- 为了确定超吸收聚合物摄入后肠道阻塞的发生率.
- 分析摄入SAP的儿科患者的临床结果,干预措施和处置情况.
- 评估幼儿摄入超吸收聚合物的安全性.
主要方法:
- 进行了一项回顾性研究,分析了向区域中毒中心报告的SAP摄入病例.
- 数据收集时间为2002年1月1日至2023年4月25日.
- 主要结局是肠道阻塞的发展,次要结局包括症状,成像,干预和处置.
主要成果:
- 在分析的217个病例中,84%涉及6岁以下的儿童.
- 没有患者出现肠道阻塞,需要住院治疗,也没有接受外体去除手术.
- 大多数患者没有经历临床影响 (54.8%) 或轻微影响 (4.1%);没有报告重大不良事件或死亡.
结论:
- 摄入超吸收聚合物似乎很少出现严重并发症,如肠道阻塞.
- 虽然在文献中存在罕见的阻塞病例,但这项研究在报告的中毒中心病例中没有发现这种结果.
- 临床医生应保持警,并使用临床判断对个体患者的评估,尽管安全性概况普遍有利.
更多相关视频
06:06Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
Published on: February 5, 2018
08:07Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
Published on: August 24, 2016
相关概念视频
Prevention of Further Absorption of Poison
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Antidotes
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
