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Updated: Jun 4, 2025

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证明非临床QTc分析的统计和药理敏感性,使用非人类灵长类动物的多费提利德剂量反应

Derek J Leishman1, David L Holdsworth2, Derek D Best1

  • 1Eli Lilly and Company, Indianapolis, United States.

Journal of pharmacological and toxicological methods
|December 17, 2024
PubMed
概括

评估非人类灵长类动物 (NHP) 的QTc延长的一步方法比传统方法更敏感和统计学上更稳健. 这种先进的技术可以准确地检测各种剂量和暴露的药物效应,改善监管提交的非临床评估.

关键词:
在每一天的时间里,做一些事情.灵长类的灵长类动物在QTc中,QTc是QTc.敏感度 敏感度 敏感度

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